张洪新
青年研究员，博士生导师
2017年获华东师范大学理学博士学位，随后入职复旦大学化学系。2024年通过复旦大学战略人才引进计划入职先进材料实验室。研究领域为活体成像分析。发表论文30余篇，引用3700余次。主持国自然面上、青年和上海市科委国际科技合作等6个项目。担任VIEW、Nano-Micro Lett.、Chin. Chem. Lett.等期刊青年编委。
获奖情况：
2024年上海市青年科技启明星
2024武汉分析+国际峰会SCINEXT青年奖
2023年度中国稀土学会自然科学一等奖（第四完成人）
2020年上海市“扬帆计划”人才项目
欢迎加盟/报考课题组博士后/硕博士研究生！
联系方式：
电子邮箱：zhanghx@fudan.edu.cn
电话：021-31249211
研究兴趣：
-功能稀土荧光探针的开发
-稀土微纳功能结构开发
-宽场及显微光学成像系统研制
-活体生物成像及检测
发表论文情况：
35. Zi-Han Chen+, Baofeng Yun+, Yanran Hou, Xiaohan Wang, Xusheng Wang, Jing Xu, Li Jiang, Ting Han, Hongxin Zhang* and Fan Zhang*, NIR-II Anti-Stokes Luminescence Nanocrystals with 1710 nm Excitation for in vivo Bioimaging, Angew. Chem. Int. Ed., 2025, 64, e202416893
34. Yanling Yang, Fengyue Wang, Shan Zhang, Hongxin Zhang, Zhen Yang, NIR-IIb-emitted Er-coordination Polymer for Logic Gates and Optical Anticounterfeiting,Nano Biomed. Eng., 2025, 17(1): 143-150.
33. Hongyu Li, Hongxin Zhang, Novel Rare Earth Near-infrared Fluorescent Probes for in vivo Multiplexed Imaging, Chem. J. Chinese Universities, 2024, 45(11), 20240181
32. Jiang Ming, Ying Chen, Han Miao, Yong Fan, Shangfeng Wang, Zihan Chen, Zhenhao Guo, Zhixiu Guo, Luyin Qi, Xusheng Wang, Baofeng Yun, Peng Pei, Haisheng He, Hongxin Zhang, Yun Tang, Dongyuan Zhao, Gary Ka-Leung Wong, Jean-Claude G. Bünzli and Fan Zhang*, High-Brightness Transition Metal-Sensitized Lanthanide Near-Infrared Luminescent Nanoparticles, Nat. Photon., 2024, 18, 1254-1262.
31. Ben Shi#, Lu Zhang#, Kui Yan, Jiang Ming, Zihan Chen, Ying Chen, Haisheng He, Hongxin Zhang, Lixin Wang, Shangfeng Wang* and Fan Zhang*, Efficient and Stable NIR-II Phosphorescence of Metallophilic Molecular Oligomers for In Vivo Single-Cell Tracking and Time-Resolved Imaging, Angew. Chem. Int. Ed., 2024, e202410118
30. Xinyan Zhu, Mingzhu Yang, Hongxin Zhang*, Over 104-fold amplified upconversion luminescence of lanthanide nanocrystals through optical oscillator-like system, Luminescence. 2024, 39, e4611.
29. Zi-Han Chen, Xiaohan Wang, Mingzhu Yang, Jiang Ming, Baofeng Yun, Lu Zhang, Xusheng Wang, Peng Yu, Jing Xu, Hongxin Zhang*, and Fan Zhang*, An Extended NIR-II Superior Imaging Window from 1500 to 1900 nm for High-Resolution In Vivo Multiplexed Imaging Based on Lanthanide Nanocrystals, Angew. Chem. Int. Ed. 2023, 62, e202311883.
28. Yiwei Yang, Ying Chen, Peng Pei, Yong Fan*, Shangfeng Wang, Hongxin Zhang, Dongyuan Zhao, Bin-zhi Qian, and Fan Zhang*, Fluorescence-Amplified Nanocrystals in the Second Near-Infrared Window For In Vivo Real-Time Dynamic Multiplexed Imaging, Nature Nanotechnology, 2023, 18, 1195-1204
27. Y. Zhan, P. Yu, X. Wang, Y. Xie*, H. Zhang*, F. Zhang*, Activatable NIR-II Lanthanides-Polymetallic Oxomolybdate Hybrid Nanosensors for Monitoring Chemotherapy Induced Enteritis, Adv. Funct. Mater. 2023, 2301683.
26. M. Zhao, A. Sik, H. Zhang*, F. Zhang, Tailored NIR-II Lanthanide Luminescent Nanocrystals for Improved Biomedical Application, Adv. Opt. Mater. 2023, 11, 2202039.
25. Ying Chen#, Peng Pei#, Yiwei Yang, Hongxin Zhang and Fan Zhang*, Noninvasive Early Diagnosing of Allograft Rejection by a Granzyme B Protease Responsive NIR-II Bioimaging Nanosensor, Angew. Chem. Int. Ed., 2023, 135, e202301696
24. X. Zhu, H. Zhang*, F. Zhang*, Expanding NIR-II Lanthanide Toolboxes for Improved Biomedical Imaging and Detection, Acc. Mater. Res. 2023, 4, 536−547
23. X. Zhu, X. Wang, H. Zhang*, F. Zhang*, Luminescence Lifetime Imaging Based on Lanthanide Nanoparticles, Angew. Chem. Int. Ed. 2022, 61, e202209378.
22. Xinyan Zhu, Hongxin Zhang*, Fan Zhang, Ligand-Based Surface Engineering of Lanthanide Nanoparticles for Bioapplications, ACS Materials Lett. 2022, 4, 1815−1830.
21. Chenzhi Yao#, Ying Chen#, Mengyao Zhao, Shangfeng Wang, Bin Wu, Yiwei Yang, Dongrui Yin, Peng Yu, Hongxin Zhang and Fan Zhang*, A Bright, Renal-Clearable NIR-II Brush Macromolecular Probe with Long Blood Circulation Time for Kidney Disease Bioimaging, Angew. Chem. Int. Ed., 2022, 61, e202114
20. Yapai Song, Mengyang Lu, Yao Xie, Guotao Sun, Jiabo Chen, Hongxin Zhang, Xin Liu,* Fan Zhang, and Lining Sun*, Deep Learning Fluorescence Imaging of Visible to NIR-II Based on Modulated Multimode Emissions Lanthanide Nanocrystals, Adv. Funct. Mater., 2022, 2206802
19. Xuan Liu#, Heming Chen#, Yiting Wang#, Yueguang Si, Hongxin Zhang, Xiaomin Li*, Zhengcheng Zhang, Biao Yan, Su Jiang, Fei Wang, Shijun Weng, Wendong Xu, Dongyuan Zhao, Jiayi Zhang* and Fan Zhang*, Near-infrared manipulation of multiple neuronal populations via trichromatic upconversion, Nature Communications, 2021, 12, 5662
18. X. Zhu, X. Liu, H. Zhang*, M. Zhao, P. Pei, Y. Chen, Y. Yang, L. Lu, P. Yu, C. Sun, J. Ming, I. Ábrahám, A. M. El-Toni, A. Khan, F. Zhang*, High-fidelity NIR-II multiplexed lifetime bioimaging with bright double interfaced lanthanide nanoparticles, Angew. Chem. Int. Ed. 2021, 60, 23545-23551.
17. Ting Wang+, Shangfeng Wang+*, Zhiyong Liu+, Zuyang He, Peng Yu, Mengyao Zhao, Hongxin Zhang, Lingfei Lu, Zhengxin Wang, Ziyu Wang, Weian Zhang*, Yong Fan, Caixia Sun, Dongyuan Zhao, Weimin Liu, Jean-Claude G. Bünzli and Fan Zhang*, A hybrid erbium(III)–bacteriochlorin near-infrared probe for multiplexed biomedical imaging, Nature Materials, 2021, 20, 1571–1578
16. Hongxin Zhang*, Mengyao Zhao, István M. Ábrahám and Fan Zhang*, Super-Resolution Imaging With Lanthanide Luminescent Nanocrystals: Progress and Prospect, Front. Bioeng. Biotechnol. 2021, 9, 692075
15. Peng Pei, Ying Chen, Caixia Sun, Yong Fan*, Yanmin Yang*, Xuan Liu, Lingfei Lu, Mengyao Zhao, Hongxin Zhang, Dongyuan Zhao, Xiaogang Liu, Fan Zhang*, X-ray-activated persistent luminescence nanomaterials for NIR-II imaging, NatureNanotechnology, 2021, 16, 1011–1018
14. Xuan Liu, Zihan Chen, Hongxin Zhang, Yong Fan*, Fan Zhang*, Independent Luminescent Lifetime and Intensity Tuning of Upconversion Nanoparticles by Gradient Doping for Multiplexed Encoding, Angew. Chem. Int. Ed., 2021, 60(13), 7041-7045
13. Mengyao Zhao+, Jianbo Wang+*, Zuhai Lei, Lingfei Lu, Shangfeng Wang, Hongxin Zhang, Benhao Li, and Fan Zhang*, NIR-II pH Sensor with FRET Adjustable Transition Point for In Situ Dynamic Tumor Microenvironment Visualization, Angew. Chem. Int. Ed., 2021, 60(10), 5091-5095
12. M. Zhao†, B. Li†, H. Zhang*, F. Zhang*, Activatable fluorescence sensors for in vivo biodetection in the second near-infrared window, Chem. Sci., 2021, 12, 3448-3459.
11. Qisong Zhang, Peng Yu, Yong Fan*, Caixia Sun, Haisheng He, Xuan Liu, Lingfei Lu, Mengyao Zhao, Hongxin Zhang, Fan Zhang*, Bright and Stable NIR‐II J‐aggregated AIE Dibodipy for Dynamic in vivo Bioimaging, Angew. Chem. Int. Ed., 2021, 60(8), 3967-3973
10. Ying Chen, Hongxin Zhang, Zuhai Lei, Fan Zhang*, Recent Advances for Intraoperative Nerve Bioimaging: Fluorescence‐Guided Surgery for Nerve Preservation, Small Structures, 2020,1, 2000036
9. H. Zhang, Z. Chen, X. Liu, F. Zhang*, A mini-review on recent progress of new sensitizers for luminescence of lanthanide doped nanomaterials. Nano Res., 2020, 13(7), 1795-1809.
8. Benhao Li+, Mengyao Zhao+, Lishuai Feng, Chaoran Dou, Suwan Ding, Gang Zhou, Lingfei Lu, Hongxin Zhang, Feiya Chen, Xiaomin Li, Guangfeng Li, Shichang Zhao, Chunyu Jiang, Yan Wang, Dongyuan Zhao, Yingsheng Cheng, Fan Zhang*, Organic NIR-II Molecule with Long Blood Half-Life for In Vivo Dynamic Vascular Imaging, Nat. Commun., 2020, 11, 3102
7. Mengyao Zhao+, Benhao Li+, Yifan Wu, Haisheng He, Xinyan Zhu, Hongxin Zhang, Chaoran Dou, Lishuai Feng, Yong Fan, Fan Zhang*, A Tumor‐Microenvironment‐Responsive Lanthanide–Cyanine FRET Sensor for NIR‐II Luminescence‐Lifetime In Situ Imaging of Hepatocellular Carcinoma, Adv. Mater., 2020, 32(28), 2001172
6. Caixia Sun+, Benhao Li+, Mengyao Zhao, Shangfeng Wang, Zuhai Lei, Lingfei Lu, Hongxin Zhang, Lishuai Feng, Chaoran Dou, Dongrui Yin, Huixiong Xu, Yingsheng Cheng, Fan Zhang*, J-aggregates of Cyanine Dye for NIR-II In-vivo Dynamic Vascular Imaging Beyond 1500 nm,J. Am. Chem. Soc., 2019, 141(49), 19221-19225
5. H. Zhang, Y. Fan, P. Pei, C. Sun, L. Lu, F. Zhang*, Tm3+-sensitized NIR-II fluorescent nanocrystals for In vivo information storage and decoding, Angew. Chem. Int. Ed.,2019, 58, 10153 -10157.
4. Hongxin Zhang, Tianqing Jia,* Long Chen, Yuchan Zhang, Shian Zhang, Donghai Feng, Zhenrong Sun and Jianrong Qiu, Depleted upconversion luminescence in NaYF4:Yb3+,Tm3+ nanoparticles via simultaneous two-wavelength excitation, Phys. Chem. Chem. Phys., 2017, 19, 17756—17764.
3. Hongxin Zhang, Tianqing Jia,* Xiaoying Shang, Shian Zhang, Zhenrong Sun and Jianrong Qiu, Mechanisms of the blue emission of NaYF4:Tm3+ nanoparticles excited by an 800 nm continuous wave laser, Phys. Chem. Chem. Phys., 2016, 18, 25905—25914.
2. Hongxin Zhang, Tianqing Jia,* Kan Zhou, Jukun Liu, Donghai Feng, Shian Zhang and Zhenrong Sun, Fabrication of gold micro/nanostructures by femtosecond laser direct writing and chemical etching, JournalofNonlinearOpticalPhysics&Materials, 2014, 23, 1450048
1. Tingyi Li, Xiaoming Qu,a Yan Zhu, Peng Sun, Hailong Yang, Hongxin Zhang, Yuqin Shan, Defu Liu, Xiang Zhang, and Jincheng Mao,* Synthesis of Diarylalkynes by Iron/Copper Co-Catalyzed Decarboxylative sp-sp2 Coupling of Alkynyl Carboxylic Acids and Aryl Halides, Adv. Synth. Catal. 2011, 353, 2731-2738
