赵梦瑶

助理教授，博士生导师，国家级青年人才

2015年于南开大学取得理学学士学位，2020年于复旦大学取得理学博士学位，随后前往新加坡国立大学从事博士后研究。2025年4月通过复旦大学人才引进计划加入先进材料实验室。以一作/通讯（含共同）在Nat. Commun.，J. Am. Chem. Soc.，Angew. Chem. Int. Ed.，Adv. Mater.， CCS Chem.等期刊发表SCI论文18篇。总发表论文40余篇，总引用大于4500次，H因子28，授权国家发明专利3项。主持国家重点研发计划青年科学家项目课题，国家自然科学青年科学基金项目（C类），新加坡卫生部研究基金（Singapore NMRC OF-YIRG）。2024年获得国家自然科学基金优秀青年科学基金项目（海外）支持。多次在国内外学术会议上作学术报告，任第二届国际分子影像与诊疗大会组秘书，Materials Futures期刊青年编委。

研究方向

近红外区光学活体成像与传感

分子探针与稀土光学探针开发

成像引导的功能核酸递送

近红外光学技术结合生物合成

招生方向

光学生物成像

荧光分子探针合成

合成生物学

欢迎上述方向的博士后或对上述方向感兴趣的博士生/硕士生/本科生加入！

联系方式

电子邮箱：myzhao@fudan.edu.cn

发表论文:

20. B.Li^#, M. Zhao^#*, B. Yang, T. Yang, Y. Wang, Y. Hu, M. Zhang, J. Ge, X. Tang, Z. Zhang, H. Cui, X. Chen, Y. Y. Yang, L. Peng, Q. Ni* Antioxidant Lipid Nanoparticles Enhance mRNA Stability for Regeneration Therapy and Gene Editing. Nat. Commun., 2026, Accepted. 

19. B. Yang^#, B. Li^#, Y. Zhu*, M. Zhao, Y. Cheng, X. Zhao, E. Deryn Teoh, Y. Wang, M. Zhang, X. Tang, S. Jin, Y. Sun, X. Zhang, B. Xue, J. Yan, G. Wu, Z. Lin, M. Luo, H. Yu, L. Zhang, X. Chen*, Q. Ni* Rational design of rigid mRNA folding architecture to enhance intracellular processing and protein production. Nat. Nanotechnol., 2026, 21, 407-418. 

18. S. Cai^#, R. Xu^#, Y. Tian^#, N. Diao, H. Li, L. Yang, Y. Zhao, X. Xu, Q. Gao, C. Zhang, Y. Miao, M. Zhao*, Q. Tang*, D. Han* A DNA Origami-Based Cobweb Facilitates Precise and Receptor-Interference Free Modification of Extracellular Vesicle Mimetic for Enhanced Delivery Efficacy. J. Am. Chem. Soc., 2026, 148, 16008-16018. 

17. B. Li, J. Wang*, Y. Peng, C. Liu, Y. Ming, B. Yang, D. He, W. Lai, L. Guo, M. Zhao*, X. Chen* BODIPY-Doped Nanocarrier Engineering (BONE) Improves Bone Marrow mRNA Delivery by NIR-II Bioimaging Guided Screening. J. Am. Chem. Soc., 2026, 148, 4966-4975. 

16. F. Zhai^#, B. Yun^#, J. Ming, T. Yu, B. Li*, X. Liu, X. Wang, Z. Chen, C. Song, M. Zhao, W. Li, Z. Liu, A. Liang*, J. Li*, Fan Zhang* Non-Invasive Diagnosis of Early Colorectal Cancerization via Amplified Sensing of MicroRNA-21 in NIR-II Window. Adv. Mater.2025, 37, 2501378. 

加入复旦前：

15. M. Zhao, W. Lai, B. Li, T. Bai, C. Liu, Y. Lin, S. An, L. Guo, L. Li, J. Wang*, F. Zhang* NIR-II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization. Angew. Chem. Int. Ed., 2024, 63, e202403968.

14. M. Zhao, X. Chen* Recent Advances in NIR-II Materials for Biomedical Applications. Acc. Mater. Res.2024, 5, 600-613.

13. M. Zhao, H. Zhuang, B. Li, M. Chen*, X. Chen* In Situ Transformable Nanoplatforms with Supramolecular Cross-Linking Triggered Complementary Function for Enhanced Cancer Photodynamic Therapy. Adv. Mater., 2023, 35, 2209944.

12. B. Li^#, M. Zhao^#, W. Lai, X. Zhang, B. Yang, X. Chen*, Q. Ni* Activatable NIR-II Photothermal Lipid Nanoparticles for Improved Messenger RNA Delivery. Angew. Chem. Int. Ed., 2023, e202302676.

11. M. Zhao, H. Zhuang, H. Zhang, B. Li, J. Ming, X. Chen*, M. Chen* A LRET Nanoplatform Consisting of Lanthanide and Amorphous Manganese Oxide for NIR-II Luminescence Lifetime Imaging of Tumor Redox Status. Angew. Chem. Int. Ed.,2022, 61, e202209592.

10. M. Zhao, A. Sik, H. Zhang*, F. Zhang* Tailored NIR-II Lanthanide Luminescent Nanocrystals for Improved Biomedical Application. Adv. Optical Mater.2022, doi: 10.1002/adom.202202039.

9. C. Sun^#, M. Zhao^#, X. Zhu, P. Pei, F. Zhang* One-pot Preparation of Highly Dispersed NIR-II J-aggregates Nanoparticles Based on FD-1080 Cyanine Dye for Bioimaging and Biosensing. CCS Chemistry, 2022, 4, 476.

8. B. Li^#, M. Zhao^#, J. Lin, P. Huang*, X. Chen* Management of Fluorescent Organic/inorganic Nanohybrids for Biomedical Applications in the NIR-II Region. Chem. Soc. Rev., 2022, 51, 7692.

7. M. Zhao^#, J. Wang^#*, Z. Lei, L. Lu, S. Wang, H. Zhang, B. Li, F. Zhang* NIR-II pH Sensor with FRET Adjustable Transition Point for In Situ Dynamic Tumor Microenvironment Visualization. Angew. Chem. Int. Ed.,2021, 60, 5091.

6. M. Zhao^#, B. Li^#, H. Zhang, F. Zhang* Activatable Fluorescence Sensors for in vivo Bio-detection in the Second Near-infrared Window. Chem. Sci., 2021, 12, 3448.

5. M. Zhao^#, B. Li^#, Y. Wu, H. He, X. Zhu, H. Zhang, C. Dou, L. Feng, Y. Fan, F. Zhang* A Tumor-Microenvironment-Responsive Lanthanide-Cyanine FRET Sensor for NIR-II Luminescence Lifetime In Situ Imaging of Hepatocellular Carcinoma. Adv. Mater., 2020, 32, 2001172.

4. B. Li^#, M. Zhao^#, L. Feng, C. Dou, G. Zhou, L. Lu, H. Zhang, F. Chen, X. Li, S. Ding, G. Li, S. Zhao, C. Jiang, Y. Wang, Y. Cheng, D. Zhao, F. Zhang* Organic NIR-II Molecule with Long Blood Half-Life for In Vivo Dynamic Vascular Imaging. Nat. Commun., 2020, 11, 3102.

3. M. Zhao^#, R. Wang^#, B. Li, Y. Fan, Y. Wu, X. Zhu, F. Zhang* Precise in vivo Inflammation Imaging Using in‐situ Responsive Cross‐linking of Glutathione Modified Ultra‐Small NIR‐II Lanthanide Nanoparticles. Angew. Chem. Int. Ed.2019, 58, 2050.

2. M. Zhao, B. Li, Y. Fan, F. Zhang* In vivo Assembly and Disassembly of Probes to Improve Near-infrared Optical Bioimaging. Adv. Health. Mater.2019, 8, 1801650.

1. M. Zhao, B. Li, P. Wang, L. Lu, Z. Zhang, L. Liu, S. Wang, D. Li, R. Wang, F. Zhang* Supramolecularly Engineered NIR-II and Upconversion Nanoparticles In-vivo Assembly and Dis-assembly to Improve Bioimaging. Adv. Mater.2018, 30, 1804982.